<?xml version="1.0" encoding="UTF-8" ?>
<rss version="2.0" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom">
	<channel>
		<title>University of Health Sciences, Cambodia</title>
		<link>http://uhscambodia.ucoz.org/</link>
		<description></description>
		<lastBuildDate>Tue, 21 Sep 2010 09:55:27 GMT</lastBuildDate>
		<generator>uCoz Web-Service</generator>
		<atom:link href="https://uhscambodia.ucoz.org/news/rss" rel="self" type="application/rss+xml" />
		
		<item>
			<title>Sickle Cell Disease (SCD) Visits to Emergency Departments (ED)</title>
			<description>FROM: http://www.cdc.gov/Features/dsSickleCell_ED_Visits/&lt;br&gt;&lt;br&gt;&lt;h3&gt;Between 1999 and 2007, approximately 197,333 sickle cell disease ED visits occurred each year.&lt;/h3&gt;&lt;h3&gt;&amp;nbsp;&lt;img src=&quot;http://www.cdc.gov/Features/dsSickleCell_ED_Visits/dsSickleCell_ED_Visits_270px.gif&quot; alt=&quot;Chart: Emergency Department Visits of Sickle Cell Disease Patients by Age, 1999-2007. 0-9 years: 12.2%; 10-19 years: 15.0%; 20-29 years: 31.1%; 30-45 years: 34.6%; 45+ years: 7.0%&quot; class=&quot;righty&quot; border=&quot;0&quot; height=&quot;297&quot; width=&quot;270&quot;&gt;&lt;/h3&gt;



 
&lt;p&gt;Sickle cell disease (SCD) is an inherited blood disorder 
characterized by the production of an altered type of hemoglobin by 
those affected by the disease. When sickle cell hemoglobin deoxygenates 
while passing through blood vessels, it polymerizes and becomes 
fibrous-like causing the red blood cell to become rigid and change 
shape, appearing sickle shaped. The altered red blood cells can clog 
blood vessels resulting in lack of oxygen to tissues and causing pain. 
R...</description>
			<content:encoded>FROM: http://www.cdc.gov/Features/dsSickleCell_ED_Visits/&lt;br&gt;&lt;br&gt;&lt;h3&gt;Between 1999 and 2007, approximately 197,333 sickle cell disease ED visits occurred each year.&lt;/h3&gt;&lt;h3&gt;&amp;nbsp;&lt;img src=&quot;http://www.cdc.gov/Features/dsSickleCell_ED_Visits/dsSickleCell_ED_Visits_270px.gif&quot; alt=&quot;Chart: Emergency Department Visits of Sickle Cell Disease Patients by Age, 1999-2007. 0-9 years: 12.2%; 10-19 years: 15.0%; 20-29 years: 31.1%; 30-45 years: 34.6%; 45+ years: 7.0%&quot; class=&quot;righty&quot; border=&quot;0&quot; height=&quot;297&quot; width=&quot;270&quot;&gt;&lt;/h3&gt;



 
&lt;p&gt;Sickle cell disease (SCD) is an inherited blood disorder 
characterized by the production of an altered type of hemoglobin by 
those affected by the disease. When sickle cell hemoglobin deoxygenates 
while passing through blood vessels, it polymerizes and becomes 
fibrous-like causing the red blood cell to become rigid and change 
shape, appearing sickle shaped. The altered red blood cells can clog 
blood vessels resulting in lack of oxygen to tissues and causing pain. 
Repeated, unpredictable episodes of acute pain are a complication of 
sickle cell disease that affect a substantial number of patients with 
the disease.&lt;/p&gt;
 
&lt;p&gt;Data from the National Hospital Ambulatory Medical Care Survey 
(NHAMCS), a survey of hospital ED and outpatient visits, for the years 
1999–2007 revealed estimates of approximately 1,475,000 (95% CI = 
1,214,000, 1,736,000) and 1,776,000 (95% CI = 1,484,000, 2,068,000) 
emergency department visits made by patients with a primary or any 
diagnosis of SCD, respectively. The estimated yearly average number of 
emergency department visits by patients with any diagnosis of SCD was 
197,333. ED visits by patients with SCD were identified using the 
International Classification of Disease, 9th Revision, Clinical 
Modification (ICD-9-CM) codes, and nationally weighted estimates were 
calculated.&lt;/p&gt;
 
&lt;img src=&quot;http://www.cdc.gov/Features/dsSickleCell_ED_Visits/dsSickleCell_ED_Visits_b340px.gif&quot; alt=&quot;Sickle Cell Disease (SCD) Patient cited reasons for visits to Emergency Department (ED), 1999-2007&quot; longdesc=&quot;longdesc1.html&quot; class=&quot;righty&quot; border=&quot;0&quot; height=&quot;335&quot; width=&quot;340&quot;&gt;

&lt;h2&gt;Reasons for ED Visits&lt;/h2&gt;

&lt;p&gt;Reasons for ED visits included chest pain (11%*), other pain or 
unspecified pain (67%), fever/infection (6%), and shortness of 
breath/breathing problem/cough (5%) among other reasons. Substantial 
numbers of ED visits occur among persons with SCD. The most common 
reason for the ED visits is pain symptoms. The findings of this study 
can help to improve health services delivery and utilization among 
patients with SCD. &lt;/p&gt;
 
&lt;h2&gt;Characteristics of ED Visits&lt;/h2&gt;

&lt;p&gt;The mode of arrival for most emergency department visits by patients 
with SCD was walk-in (79%), followed by ambulance (14%; Table 1). The 
mode of arrival was walk-in for 87% of visits by patients aged 0–19 
years, and 76% of visits by patients aged ≥20 years. The age groups with
 largest percentage of ED visits were 20-29 years and 30-45 years, and 
the age group with the fewest visits was &amp;gt;45 years. &lt;/p&gt;
 

&lt;img src=&quot;http://www.cdc.gov/Features/dsSickleCell_ED_Visits/dsSickleCell_ED_Visits_c500px.gif&quot; alt=&quot;Characteristics: Emergency Department Visits of Sickle Cell Disease Patients, 1999-2007&quot; longdesc=&quot;longdesc2.html&quot; border=&quot;0&quot; height=&quot;591&quot; width=&quot;500&quot;&gt;

&lt;p&gt;The expected source of payment for emergency department visits by 
patients with SCD was private insurance, Medicaid/State Children&apos;s 
Health Insurance Program (SCHIP), Medicare, and other or unknown for 
14%, 58%, 14%, and 15% of visits, respectively. Among visits by patients
 aged 0 –19 years, the expected source of payment was private insurance 
for 20% and Medicaid or SCHIP for 70%. Among visits by patients aged20 
years, the expected source of payment was private insurance for 11%, 
Medicare for 19%, and Medicaid for 53%. &lt;/p&gt;
 
&lt;p&gt;The percentage of visits indicated to be initial visit, follow-up 
visit, and unknown as to the episode of care were 66%, 23%, and 11%, 
respectively (Table 1). Among visits by patients aged ≥20 years, the 
episode of care was indicated as a follow-up visit for 27% of the 
visits. Approximately 29% of emergency department visits by patients 
with SCD resulted in hospital admission. This was 37% among visits by 
patients aged 0–19 years, and 26% among visits by patients aged ≥20 
years. The difference by age group in the percentage admitted to the 
hospital came close to but did not reach significance (p=0.059). &lt;/p&gt;
 
&lt;p&gt;*All statistics listed in this feature under Reasons for ED Visits 
and Characteristics of ED Visits have been rounded to the nearest whole 
number. Co statistics can be found in the charts on this page.&lt;/p&gt;
 
&lt;h4&gt;Data Source&lt;/h4&gt;
 
&lt;p&gt;Yusuf HR, Atrash HK, Grosse SD, Parker CS, Grant AM. &lt;a class=&quot;external noDecoration&quot; href=&quot;http://www.ajpm-online.net/webfiles/images/journals/amepre/S536.pdf&quot;&gt;&lt;span class=&quot;tp-label&quot;&gt;Emergency Department visits made by patients with sickle cell disease: a descriptive study, 1999-2007&lt;/span&gt;&lt;span class=&quot;plugIns&quot;&gt;&amp;nbsp;&lt;img src=&quot;http://www.cdc.gov/TemplatePackage/images/icon_pdf.gif&quot; alt=&quot;Adobe PDF file&quot; title=&quot;Adobe PDF file&quot; class=&quot;plugin&quot; border=&quot;0&quot;&gt;&amp;nbsp;[PDF - 100 KB]&lt;/span&gt;&lt;img src=&quot;http://www.cdc.gov/TemplatePackage/images/icon_out.png&quot; title=&quot;External Web Site Icon&quot; alt=&quot;External Web Site Icon&quot; class=&quot;externalImg&quot;&gt;&lt;/a&gt;. &lt;em&gt;Am J Prev Med&lt;/em&gt; 2010;38(4S):S536–S541.&lt;/p&gt;</content:encoded>
			<link>https://uhscambodia.ucoz.org/news/sickle_cell_disease_scd_visits_to_emergency_departments_ed/2010-09-21-13</link>
			<category>External</category>
			<dc:creator>mozachsz</dc:creator>
			<guid>https://uhscambodia.ucoz.org/news/sickle_cell_disease_scd_visits_to_emergency_departments_ed/2010-09-21-13</guid>
			<pubDate>Tue, 21 Sep 2010 09:55:27 GMT</pubDate>
		</item>
		<item>
			<title>Attention Deficit Hyperactivity Disorder: What Is ADHD?</title>
			<description>&lt;p&gt;FROM: http://www.webmd.com/add-adhd/guide/attention-deficit-hyperactivity-disorder-adhd&lt;br&gt;&lt;/p&gt;&lt;p&gt;Attention-deficit/hyperactivity disorder (&lt;a href=&quot;http://www.webmd.com/add-adhd/default.htm&quot;&gt;ADHD&lt;/a&gt;) is also known as
hyperactivity or attention deficit disorder (ADD). ADHD is a common condition
that affects children and adolescents, while ADD is more common in adults.&lt;/p&gt;
 &lt;p&gt;The National Institute of Mental Health (NIMH) estimates that 3% to 5% of
children have ADHD. Some experts, though, says ADHD may occurs in 8% to 10% of
school age children. Experts also question whether kids really outgrow ADHD.
What that means is that this disorder may be more common in adults than
previously thought.&lt;/p&gt;
 &lt;p&gt;Children with ADHD generally have problems paying attention or
concentrating. They can&apos;t seem to follow directions and are easily bored or
frustrated with tasks. They also tend to move constantly and are impulsive, not
stopping to think before they act. These behaviors are generally com...</description>
			<content:encoded>&lt;p&gt;FROM: http://www.webmd.com/add-adhd/guide/attention-deficit-hyperactivity-disorder-adhd&lt;br&gt;&lt;/p&gt;&lt;p&gt;Attention-deficit/hyperactivity disorder (&lt;a href=&quot;http://www.webmd.com/add-adhd/default.htm&quot;&gt;ADHD&lt;/a&gt;) is also known as
hyperactivity or attention deficit disorder (ADD). ADHD is a common condition
that affects children and adolescents, while ADD is more common in adults.&lt;/p&gt;
 &lt;p&gt;The National Institute of Mental Health (NIMH) estimates that 3% to 5% of
children have ADHD. Some experts, though, says ADHD may occurs in 8% to 10% of
school age children. Experts also question whether kids really outgrow ADHD.
What that means is that this disorder may be more common in adults than
previously thought.&lt;/p&gt;
 &lt;p&gt;Children with ADHD generally have problems paying attention or
concentrating. They can&apos;t seem to follow directions and are easily bored or
frustrated with tasks. They also tend to move constantly and are impulsive, not
stopping to think before they act. These behaviors are generally common in
children. But they occur more often than usual and are more severe in a child
with ADHD.&lt;/p&gt;
 &lt;p&gt;The behaviors that are common with ADHD interfere with a child&apos;s ability to
function at school and at home.&lt;/p&gt;
 &lt;p&gt;Adults with ADHD may have difficulty with time management, organizational
skills, goal setting, and employment. They may also have problems with
relationships, self-esteem, and addictions.&lt;/p&gt;
 &lt;h3&gt;What are ADHD symptoms in children?&lt;/h3&gt;
 &lt;p&gt;Symptoms of ADHD in children are generally grouped into three categories:
inattention, hyperactivity, and impulsiveness.&lt;/p&gt;
 &lt;p&gt;
 &lt;b&gt;Inattention --&lt;/b&gt; A child with ADHD:&lt;/p&gt;
 &lt;ul&gt;&lt;li&gt;is easily distracted&lt;/li&gt;&lt;li&gt;does not follow directions or finish tasks&lt;/li&gt;&lt;li&gt;does not appear to be listening when someone is speaking&lt;/li&gt;&lt;li&gt;does not pay attention and makes careless mistakes&lt;/li&gt;&lt;li&gt;is forgetful about daily activities&lt;/li&gt;&lt;li&gt;has problems organizing daily tasks&lt;/li&gt;&lt;li&gt;avoids or dislikes activities that require sitting still or a sustained
effort&lt;/li&gt;&lt;li&gt;often loses things, including personal items&lt;/li&gt;&lt;li&gt;has a tendency to daydream&lt;/li&gt;&lt;/ul&gt;
 &lt;p&gt;
 &lt;b&gt;Hyperactivity --&lt;/b&gt; A child with ADHD:&lt;/p&gt;
 &lt;ul&gt;&lt;li&gt;often squirms, fidgets, or bounces when sitting&lt;/li&gt;&lt;li&gt;does not stay seated as expected&lt;/li&gt;&lt;li&gt;has difficulty playing quietly&lt;/li&gt;&lt;li&gt;is always moving, such as running or climbing on things (In &lt;a href=&quot;http://children.webmd.com/tc/growth-and-development-ages-15-to-18-years-promoting-healthy-growth-and-development&quot;&gt;teens&lt;/a&gt; and adults, this is more
commonly described as a sense of restlessness)&lt;/li&gt;&lt;li&gt;talks excessively&lt;/li&gt;&lt;/ul&gt;
 &lt;p&gt;
 &lt;b&gt;Impulsivity --&lt;/b&gt; A child with ADHD:&lt;/p&gt;
 &lt;ul&gt;&lt;li&gt;has difficulty waiting for his or her turn&lt;/li&gt;&lt;li&gt;blurts out answers before the question has been completed&lt;/li&gt;&lt;li&gt;often interrupts others&lt;/li&gt;&lt;/ul&gt;
 &lt;p&gt;For in depth information, see WebMD&apos;s &lt;a href=&quot;http://www.webmd.com/add-adhd/ast_oneadhd-children&quot;&gt;ADHD in
Children&lt;/a&gt;.&lt;/p&gt;
 &lt;h3&gt;What are ADHD symptoms in adults?&lt;/h3&gt;
 &lt;p&gt;Adult ADHD symptoms may be different than the symptoms in children. In
addition, they may stem directly from ADHD or may be the result of behavioral
issues. Symptoms include:&lt;/p&gt;
 &lt;ul&gt;&lt;li&gt;chronic lateness and forgetfulness&lt;/li&gt;&lt;li&gt;
 &lt;a href=&quot;http://www.webmd.com/anxiety-panic/default.htm&quot;&gt;anxiety&lt;/a&gt;
 &lt;/li&gt;&lt;li&gt;low self-esteem&lt;/li&gt;&lt;li&gt;employment problems&lt;/li&gt;&lt;li&gt;difficulty controlling anger&lt;/li&gt;&lt;li&gt;impulsiveness&lt;/li&gt;&lt;li&gt;substance abuse or &lt;a href=&quot;http://www.webmd.com/mental-health/alcohol-abuse/alcohol-and-drug-problems-topic-overview&quot;&gt;
addiction&lt;/a&gt;&lt;/li&gt;&lt;li&gt;poor organization skills&lt;/li&gt;&lt;li&gt;procrastination&lt;/li&gt;&lt;li&gt;low frustration tolerance&lt;/li&gt;&lt;li&gt;chronic boredom&lt;/li&gt;&lt;li&gt;difficulty concentrating when reading&lt;/li&gt;&lt;li&gt;mood swings&lt;/li&gt;&lt;li&gt;
 &lt;a href=&quot;http://www.webmd.com/depression/default.htm&quot;&gt;depression&lt;/a&gt;
 &lt;/li&gt;&lt;li&gt;relationship problems&lt;/li&gt;&lt;/ul&gt;
 &lt;p&gt;For in depth information, see WebMD&apos;s &lt;a href=&quot;http://www.webmd.com/add-adhd/guide/adhd-adults&quot;&gt;Adult ADHD&lt;/a&gt;.&lt;/p&gt;
 &lt;h3&gt;What causes ADHD?&lt;/h3&gt;
 &lt;p&gt;The exact cause of ADHD is not known, although researchers continue to study
the brain for clues. They suspect that there are several factors that may
contribute to the condition, including:&lt;/p&gt;
 &lt;ul&gt;&lt;li&gt;
 &lt;b&gt;Heredity&lt;/b&gt;: The fact that ADHD tends to run in families suggests that
children may inherit a tendency to develop ADHD from their parents.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Chemical imbalance&lt;/b&gt;: Experts believe an imbalance of brain chemicals
(neurotransmitters) that transmit nerve impulses may be a factor in the
development of ADHD symptoms.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Brain changes&lt;/b&gt;: Areas of the brain that control attention are less
active in children with ADHD than in children without ADHD.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Head injury&lt;/b&gt;:There are reports of children with head injuries,
particularly with concussions, developing behavioral problems that may mimic
ADHD.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Poor &lt;a href=&quot;http://www.webmd.com/diet/default.htm&quot;&gt;nutrition&lt;/a&gt;, infections, and
substance abuse (including cigarette and alcohol use) during &lt;a href=&quot;http://www.webmd.com/baby/default.htm&quot;&gt;pregnancy&lt;/a&gt;&lt;/b&gt; may be contributing factors. That&apos;s because
they can affect the development of the baby&apos;s brain.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Exposure to toxins, such as lead or PCBs, in early childhood&lt;/b&gt; can
also affect brain development.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Injury to the brain or a brain disorder&lt;/b&gt; may play a part in the
development of ADHD.&lt;/li&gt;&lt;/ul&gt;
 &lt;p&gt;Eating too much sugar does not cause a child to develop ADHD. A proper diet
is essential, though, for normal development in children. ADHD is also not
caused by watching too much TV, a poor home life, poor schools, or food &lt;a href=&quot;http://www.webmd.com/allergies/default.htm&quot;&gt;allergies&lt;/a&gt;.&lt;/p&gt;
 &lt;h3&gt;How common is ADHD?&lt;/h3&gt;
 &lt;p&gt;ADHD is the most commonly diagnosed mental disorder of children and is more
common in boys than in girls. It most often is discovered during the early
school years, when a child begins to have problems paying attention. ADHD can
continue into the teen years and on into adulthood.&lt;/p&gt;
 &lt;h3&gt;How is ADHD diagnosed?&lt;/h3&gt;
 &lt;p&gt;If symptoms are present, the doctor will begin an evaluation by taking a
complete medical history and doing a physical examination. There are no
laboratory tests for ADHD. The doctor, though, may use various tests -- such as
X-rays and blood tests -- to determine if there is a physical disorder or other
problem causing the symptoms.&lt;/p&gt;
 &lt;p&gt;Certain mental illnesses, such as &lt;a href=&quot;http://www.webmd.com/depression/default.htm&quot;&gt;depression&lt;/a&gt; and &lt;a href=&quot;http://www.webmd.com/anxiety-panic/default.htm&quot;&gt;anxiety&lt;/a&gt; disorders, have some symptoms that are similar to
those of ADHD. For that reason, a complete psychiatric assessment is needed to
accurately diagnosis ADHD.&lt;/p&gt;
 &lt;p&gt;If no physical disorder is found, the child may be referred to a specialist
in childhood development disorders. That may be a child and adolescent
psychiatrist or psychologist, a pediatric neurologist, a developmental
pediatrician, or another health professional. It should be someone specially
trained to diagnose and treat ADHD. The doctor bases his or her diagnosis on
the child&apos;s symptoms and behavior. The doctor may ask for input from the
child&apos;s parents, teachers, and other adults who are familiar with the child&apos;s
symptoms.&lt;/p&gt;
 &lt;p&gt;Researchers all agree that ADHD is not an adult-onset disorder. To be ADHD,
it must be verified as being present from childhood. Adults who are thought to
have ADHD will be asked questions about their childhood. In particular, they
will be asked about such things as:&lt;/p&gt;
 &lt;ul&gt;&lt;li&gt;behavior&lt;/li&gt;&lt;li&gt;development&lt;/li&gt;&lt;li&gt;relationships&lt;/li&gt;&lt;li&gt;achievement&lt;/li&gt;&lt;li&gt;grades&lt;/li&gt;&lt;/ul&gt;
 &lt;p&gt;The answers will help the doctor make an accurate ADHD diagnosis.&lt;/p&gt;
 &lt;p&gt;For in depth information, see WebMD&apos;s &lt;a href=&quot;http://www.webmd.com/add-adhd/diagnosing-adhd&quot;&gt;ADHD Diagnosis&lt;/a&gt;.&lt;/p&gt;
 &lt;h3&gt;What is the treatment for ADHD?&lt;/h3&gt;
 &lt;p&gt;ADHD cannot be cured. But many of the symptoms that interfere with
functioning and cause distress can be controlled. Treatment for ADHD often
includes a combination of medication and various psychosocial therapies.&lt;/p&gt;&lt;p&gt;
 &lt;b&gt;Medication&lt;/b&gt;: Certain medications called stimulants may be used to help
control hyperactivity and impulsive behavior and increase attention span.
Commonly used stimulants include:&lt;/p&gt;
 &lt;ul&gt;&lt;li&gt;Concerta&lt;/li&gt;&lt;li&gt;Dexedrine&lt;/li&gt;&lt;li&gt;Focalin&lt;/li&gt;&lt;li&gt;Metadate&lt;/li&gt;&lt;li&gt;Methylin&lt;/li&gt;&lt;li&gt;Ritalin&lt;/li&gt;&lt;li&gt;Vyvanse&lt;/li&gt;&lt;/ul&gt;
 &lt;p&gt;Some children with ADHD respond to antidepressant medications such as &lt;a href=&quot;http://www.webmd.com/drugs/drug-13509-Wellbutrin+Oral.aspx?drugid=13509&amp;amp;drugname=Wellbutrin+Oral&quot;&gt;Wellbutrin&lt;/a&gt;.&lt;/p&gt;
 &lt;p&gt;Sometime stimulant drugs have worrisome side effects for children. In that
case, non stimulant medications such as &lt;a href=&quot;http://www.webmd.com/drugs/drug-64629-Strattera+Oral.aspx?drugid=64629&amp;amp;drugname=Strattera+Oral&quot;&gt;Strattera&lt;/a&gt; may be prescribed for children with ADHD who
are older than 6. Strattera is a selective norepinephrine reuptake
inhibitor.&lt;/p&gt;
 &lt;p&gt;
 &lt;b&gt;Psychosocial therapies:&lt;/b&gt; These are treatment approaches that focus on
the behavioral, psychological, social, and work/school problems associated with
the illness. Psychosocial therapies that may be used for ADHD include:&lt;/p&gt;
 &lt;ul&gt;&lt;li&gt;
 &lt;b&gt;Special education&lt;/b&gt;: Special education is a type of education that is
structured to meet a child&apos;s unique educational needs. Children with ADHD
generally benefit most from a highly structured environment and use of
routines.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Behavior modification&lt;/b&gt;: Behavior modification includes strategies for
supporting good behavior and decreasing a child&apos;s problem behavior.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Psychotherapy (counseling)&lt;/b&gt;: Psychotherapy can help a child or adult
with ADHD learn better ways to handle their emotions and frustration. It can
also help improve their self-esteem. Counseling may help family members better
understand the child or adult with ADHD.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Social skills training&lt;/b&gt;: Social skills training can help a child
learn new behaviors, such as taking turns and sharing. This will enable the
child to better function in social situations.&lt;/li&gt;&lt;li&gt;
 &lt;b&gt;Support groups&lt;/b&gt;: Support groups are generally made up of people with
similar problems and needs. This can help with acceptance and support. Groups
also can provide a forum for learning more about a disorder and the latest
approaches to treatment. These groups are helpful for adults with ADHD or
parents of children with ADHD.&lt;/li&gt;&lt;/ul&gt;
 &lt;p&gt;For in depth information, see WebMD&apos;s &lt;a href=&quot;http://www.webmd.com/add-adhd/adhd-treatment-overview&quot;&gt;ADHD
Treatment&lt;/a&gt;.&lt;/p&gt;
 &lt;h3&gt;What is the outlook for children and adults with ADHD?&lt;/h3&gt;
 &lt;p&gt;It is very important for children and adults with symptoms of ADHD to seek
professional care. Without treatment, ADHD can interfere with a child&apos;s
performance in school as well as the child&apos;s ability to make and keep friends.
This can have a negative impact on the child&apos;s self-esteem.&lt;/p&gt;
 &lt;p&gt;In addition, children with ADHD are at risk for developing conduct disorder,
depression, or an anxiety disorder. They are also more likely to have a
learning disorder. Teens with ADHD are at greater risk for car accidents, early
pregnancy, and tobacco and alcohol use. Adults with ADHD have difficulty with
time management, employment, and relationships.&lt;/p&gt;
 &lt;p&gt;But, when treated, most people with ADHD -- between 70% and 80% --
experience at least some relief of symptoms. Many of the symptoms of ADHD
diminish by early adulthood. However, up to 50% of people with ADHD as children
continue to have problems as adults.&lt;/p&gt;&lt;h3&gt;Is there a way to prevent ADHD?&lt;/h3&gt;
 &lt;p&gt;ADHD cannot be prevented or cured. However, early identification and
diagnosis, as well as a carefully designed treatment and education plan, can
help a child or adult with ADHD adjust to the disorder. Many people with ADHD
learn to focus their attention, develop their personal strengths, minimize
disruptive behavior, and become productive and successful.&lt;/p&gt;</content:encoded>
			<link>https://uhscambodia.ucoz.org/news/attention_deficit_hyperactivity_disorder_what_is_adhd/2010-09-21-12</link>
			<category>External</category>
			<dc:creator>mozachsz</dc:creator>
			<guid>https://uhscambodia.ucoz.org/news/attention_deficit_hyperactivity_disorder_what_is_adhd/2010-09-21-12</guid>
			<pubDate>Tue, 21 Sep 2010 09:47:12 GMT</pubDate>
		</item>
		<item>
			<title>Cambodia opens first methadone clinic for heroin users</title>
			<description>FROM: http://www.bbc.co.uk/news/world-asia-pacific-11310931&lt;br&gt;&lt;br&gt;&lt;span class=&quot;byline&quot;&gt;
 &lt;span class=&quot;byline-name&quot;&gt;By Guy De Launey&lt;/span&gt;
 &lt;span class=&quot;byline-title&quot;&gt;BBC News, Phnom Penh&lt;br&gt;&lt;br&gt;&lt;/span&gt;
 &lt;/span&gt;
 
 &lt;div class=&quot;caption body-narrow-width&quot;&gt;
 &lt;img src=&quot;http://news.bbcimg.co.uk/media/images/49107000/jpg/_49107387_008394563-1.jpg&quot; alt=&quot;Drug addict drinking a measure of the drug methadone (file photo)&quot; height=&quot;171&quot; width=&quot;304&quot;&gt;

 &lt;span style=&quot;width: 304px;&quot;&gt;Methadone is a heroin substitute used to treat withdrawal symptoms&lt;/span&gt;
 &lt;/div&gt;
 &lt;p class=&quot;introduction&quot;&gt;Cambodia has launched the country&apos;s first methadone-treatment programme, in a new approach to help heroin users.&lt;/p&gt;
 &lt;p&gt;The World Health Organization (WHO) told the BBC that 
addiction was widely viewed in Cambodia as a social problem, rather than
 a health issue. &lt;/p&gt;
 &lt;p&gt;Until now the government has favoured treatment centres which emphasise hard work and exercise. &lt;/p&gt;
 &lt;p&gt;But health workers and human rights grou...</description>
			<content:encoded>FROM: http://www.bbc.co.uk/news/world-asia-pacific-11310931&lt;br&gt;&lt;br&gt;&lt;span class=&quot;byline&quot;&gt;
 &lt;span class=&quot;byline-name&quot;&gt;By Guy De Launey&lt;/span&gt;
 &lt;span class=&quot;byline-title&quot;&gt;BBC News, Phnom Penh&lt;br&gt;&lt;br&gt;&lt;/span&gt;
 &lt;/span&gt;
 
 &lt;div class=&quot;caption body-narrow-width&quot;&gt;
 &lt;img src=&quot;http://news.bbcimg.co.uk/media/images/49107000/jpg/_49107387_008394563-1.jpg&quot; alt=&quot;Drug addict drinking a measure of the drug methadone (file photo)&quot; height=&quot;171&quot; width=&quot;304&quot;&gt;

 &lt;span style=&quot;width: 304px;&quot;&gt;Methadone is a heroin substitute used to treat withdrawal symptoms&lt;/span&gt;
 &lt;/div&gt;
 &lt;p class=&quot;introduction&quot;&gt;Cambodia has launched the country&apos;s first methadone-treatment programme, in a new approach to help heroin users.&lt;/p&gt;
 &lt;p&gt;The World Health Organization (WHO) told the BBC that 
addiction was widely viewed in Cambodia as a social problem, rather than
 a health issue. &lt;/p&gt;
 &lt;p&gt;Until now the government has favoured treatment centres which emphasise hard work and exercise. &lt;/p&gt;
 &lt;p&gt;But health workers and human rights groups have criticised the facilities, describing them as &quot;labour camps&quot;. &lt;/p&gt;
 &lt;p&gt;The opening of the methadone clinic is the culmination of 
years of gentle persuasion by organisations which work with drug users. &lt;/p&gt;
 &lt;span class=&quot;cross-head&quot;&gt;Ongoing concerns&lt;/span&gt;
 &lt;p&gt;The methadone programme will be strictly voluntary. Methadone is a heroin substitute used to treat withdrawal symptoms.&lt;/p&gt;
 &lt;p&gt;Two organisations which run outreach programmes for drug users will identify candidates for treatment. &lt;/p&gt;
 &lt;p&gt;If they&apos;re willing, they will be taken to the clinic for an 
assessment based on international standards. While the facility is 
supported by the WHO, it is run by the Ministry of Health inside a 
public hospital. &lt;/p&gt;
 &lt;p&gt;But while international health workers are delighted with the
 new approach, they are still concerned about the existing drug 
treatment facilities. &lt;/p&gt;
 &lt;p&gt;The government has no plans to close the centres which it says are voluntary, but which the UN has described as compulsory. &lt;/p&gt;
 &lt;p&gt;Some residents have complained of being held against their will - and forced to take experimental herbal remedies. &lt;/p&gt;</content:encoded>
			<link>https://uhscambodia.ucoz.org/news/cambodia_opens_first_methadone_clinic_for_heroin_users/2010-09-21-11</link>
			<category>Cambodia-External</category>
			<dc:creator>mozachsz</dc:creator>
			<guid>https://uhscambodia.ucoz.org/news/cambodia_opens_first_methadone_clinic_for_heroin_users/2010-09-21-11</guid>
			<pubDate>Tue, 21 Sep 2010 09:15:06 GMT</pubDate>
		</item>
		<item>
			<title>Health Inequity Slows Decline in Child Mortality</title>
			<description>&lt;span class=&quot;texto1&quot;&gt;FROM: http://ipsnews.net/news.asp?idnews=52908&lt;br&gt;&lt;br&gt;&lt;/span&gt;&lt;span class=&quot;marron&quot;&gt;By Marwaan Macan-Markar&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;texto1&quot;&gt; &lt;br&gt;&lt;b&gt;BANGKOK, Sep 21 , 2010 (IPS) - Cambodia’s partial success in reducing child mortality rates 
has exposed a fault line of inequity, one that underscores the 
advantage that the country’s urban population has had over the 
rural poor.&lt;/b&gt;&lt;br&gt;&lt;br&gt; Yet the South-east Asian kingdom, 35 percent of whose 14 
million population live below the poverty line, is not alone 
in having this mixed record of reducing child mortality, say 
child rights experts.
&lt;br&gt;&lt;br&gt;
 Some of the other countries in the region reflect a 
similar trend 10 years after world leaders committed to meet 
a set of eight targets to help the world’s poor by 2015. The 
fourth of the eight U.N. Millennium Development Goals (MDGs) 
seeks to achieve a two-thirds reduction in child mortality 
rates by 2015.
&lt;br&gt;&lt;br&gt;
 &quot;To be fair to governments in South-east Asia, chil...</description>
			<content:encoded>&lt;span class=&quot;texto1&quot;&gt;FROM: http://ipsnews.net/news.asp?idnews=52908&lt;br&gt;&lt;br&gt;&lt;/span&gt;&lt;span class=&quot;marron&quot;&gt;By Marwaan Macan-Markar&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;texto1&quot;&gt; &lt;br&gt;&lt;b&gt;BANGKOK, Sep 21 , 2010 (IPS) - Cambodia’s partial success in reducing child mortality rates 
has exposed a fault line of inequity, one that underscores the 
advantage that the country’s urban population has had over the 
rural poor.&lt;/b&gt;&lt;br&gt;&lt;br&gt; Yet the South-east Asian kingdom, 35 percent of whose 14 
million population live below the poverty line, is not alone 
in having this mixed record of reducing child mortality, say 
child rights experts.
&lt;br&gt;&lt;br&gt;
 Some of the other countries in the region reflect a 
similar trend 10 years after world leaders committed to meet 
a set of eight targets to help the world’s poor by 2015. The 
fourth of the eight U.N. Millennium Development Goals (MDGs) 
seeks to achieve a two-thirds reduction in child mortality 
rates by 2015.
&lt;br&gt;&lt;br&gt;
 &quot;To be fair to governments in South-east Asia, child 
mortality rates are going down everywhere,&quot; said Ben 
Phillips, director of strategy at the Asia office of Save 
the Children, a British-based humanitarian organisation. 
&quot;But the rate of decline is less than the rate they 
committed in 2000.&quot;
&lt;br&gt;&lt;br&gt;
 &quot;In South-east Asia, child mortality rates have almost 
halved from 2000 levels,&quot; he told IPS. &quot;But the region is 
substantially behind from meeting the two-thirds target, 
which is five years away.&quot;
&lt;br&gt;&lt;br&gt;
 A recent report by Save the Children, entitled ‘A Fair 
Chance At Life’, shows that Cambodia has seen a 32 percent 
drop in child mortality figures among the country’s &quot;richest 
20 percent&quot;, but only an 18 percent reduction in child 
mortality among the &quot;poorest 20 percent&quot;.
&lt;br&gt;&lt;br&gt;
 Indonesia, the region’s giant where 16 percent of its 225 
million people live below the poverty line, has recorded 
&quot;equitable progress,&quot; noted the 37-page report. The poorest 
20 percent has seen child mortality figures drop by 29 
percent, while the richest 20 percent has witnessed a nine 
percent decline.
&lt;br&gt;&lt;br&gt;
 Military-ruled Burma, also known as Myanmar, lags behind 
all with the worst child mortality figures. It reportedly 
has 104 children under five years dying for every 1,000 live 
births. Cambodia, by contrast, has 82 deaths of children 
under five years of age per 1,000 live births. Laos, the 
third of this region’s poorest countries, has 75 deaths per 
1,000 live births.
&lt;br&gt;&lt;br&gt;
 Child rights groups have hailed Thailand, Malaysia and 
Vietnam as being well on course to meeting the 2015 targets. 
The region’s richest country, the city-state of Singapore, 
has been singled out in a study by ‘The Lancet’, a British 
medical journal, as leading all countries in the world in 
child mortality rates, having reduced it by 75 percent since 
1990.
&lt;br&gt;&lt;br&gt;
 The inequity in child mortality rates in countries like 
Cambodia and the Philippines, which has 32 deaths per 1,000 
live births, is &quot;partly an urban-rural divide,&quot; said 
Phillips. &quot;There is no conscious discrimination, but a 
natural tendency for nurses and doctors to work in cities.&quot;
&lt;br&gt;&lt;br&gt;
 At times, the distance to a health care is a day away, 
making it costly and time consuming for a family to take a 
newborn to treat illnesses that lead to child deaths, such 
as pneumonia, diarrhoea and sepsis.
&lt;br&gt;&lt;br&gt;
 &quot;If you live more distant from a health centre, you will 
be reached later unlike those who live closer to health care 
workers,&quot; said Basil Rodriques, regional adviser for your 
child survival and development at the Asia office of the 
United Nations Children’s Fund (UNICEF). &quot;The MDGs saw the 
‘low hanging fruits’ reached first.&quot;
&lt;br&gt;&lt;br&gt;
 To address this trend, countries in the region are being 
urged to strengthen community health initiatives in rural 
areas, including by tapping trained midwives who live in the 
villages they grew up in. &quot;This is what is going to make the 
difference,&quot; Rodriques said in an interview. &quot;Governments 
are looking at how to train workers who grow up and return 
to live in their communities.&quot;&lt;br&gt;&lt;br&gt;
 Early diagnosis of diseases like pneumonia is key to 
saving a child’s life, adds Rodriques, pointing to 
achievements in Indonesia. &quot;There is a growing recognition 
of a community-focused approach, since community health 
workers are trained to see the problem and offer prompt 
care.&quot;
&lt;br&gt;&lt;br&gt;
 Vietnam’s success with a similar community health care 
programme across its rural regions is also being held up as 
another model for the region. Its record of child mortality 
is 17 deaths for 1,000 live births.
&lt;br&gt;&lt;br&gt;
 &quot;It is really hard to divorce equity from the development 
paradigm,&quot; said Rodriques. &quot;The MDGs have, in a sense, acted 
as accelerator for governments in South-east Asia to invest 
more.&quot;
&lt;br&gt;&lt;br&gt;
 Save the Children’s Phillips estimates that the entire 
Asian region needs two million health workers, ranging from 
midwives, nurses and obstetricians, to meet the 2015 targets 
on child mortality. &quot;India will need one million of them and 
South-east Asia will need a third,&quot; he said.
&lt;br&gt;&lt;br&gt;
 &quot;This requires a dramatic shift in policy and resources 
made available to strengthen rural health care systems,&quot; he 
explained. &quot;If you are not focused on equity, the outcome 
will be inequitable.&quot;
&lt;br&gt;&lt;br&gt;
 &quot;Health workers don’t just cure; they also prevent,&quot; he 
said. &quot;Governments need to be putting more people through 
nursing schools.&quot;
 (END)&lt;/span&gt;&lt;br&gt;</content:encoded>
			<link>https://uhscambodia.ucoz.org/news/health_inequity_slows_decline_in_child_mortality/2010-09-21-10</link>
			<category>Cambodia-External</category>
			<dc:creator>mozachsz</dc:creator>
			<guid>https://uhscambodia.ucoz.org/news/health_inequity_slows_decline_in_child_mortality/2010-09-21-10</guid>
			<pubDate>Tue, 21 Sep 2010 09:04:38 GMT</pubDate>
		</item>
		<item>
			<title>WHO warns countries to act against drug-resistant bacteria</title>
			<description>&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;FROM: http://www.guardian.co.uk/society/sarah-boseley-global-health/2010/aug/20/drug-resistance-infectiousdiseases&lt;br&gt;&lt;/p&gt;&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;Drug-resistance
 could put an end to the antibiotic era. The World Health Organisation 
today tells all countries they must act on hygiene and infection control&lt;/p&gt;
 
 
 
 
 
 
 


&lt;div id=&quot;content&quot;&gt;

 
 
 


 





 
 

 



 
 

 &lt;div id=&quot;article-wrapper&quot;&gt;

 
 &lt;img src=&quot;http://static.guim.co.uk/sys-images/Guardian/Pix/pictures/2009/4/14/1239726486138/Escherichia-coli-bacteria-001.jpg&quot; alt=&quot;Escherichia coli bacteria (E. coli)&quot; height=&quot;276&quot; width=&quot;460&quot;&gt;
 Scanning electron micrograph of Escherichia coli bacteria (E. coli). Photograph: S. Lowry/University of Ulster/Getty
 
 
 &lt;p&gt;The &lt;a href=&quot;http://www.who.int/&quot;&gt;World Health Organisation&lt;/a&gt; is 
today urging countries to take action against the spread of 
drug-resistant bacteria, which threaten to deprive us of antibiotics 
whi...</description>
			<content:encoded>&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;FROM: http://www.guardian.co.uk/society/sarah-boseley-global-health/2010/aug/20/drug-resistance-infectiousdiseases&lt;br&gt;&lt;/p&gt;&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;Drug-resistance
 could put an end to the antibiotic era. The World Health Organisation 
today tells all countries they must act on hygiene and infection control&lt;/p&gt;
 
 
 
 
 
 
 


&lt;div id=&quot;content&quot;&gt;

 
 
 


 





 
 

 



 
 

 &lt;div id=&quot;article-wrapper&quot;&gt;

 
 &lt;img src=&quot;http://static.guim.co.uk/sys-images/Guardian/Pix/pictures/2009/4/14/1239726486138/Escherichia-coli-bacteria-001.jpg&quot; alt=&quot;Escherichia coli bacteria (E. coli)&quot; height=&quot;276&quot; width=&quot;460&quot;&gt;
 Scanning electron micrograph of Escherichia coli bacteria (E. coli). Photograph: S. Lowry/University of Ulster/Getty
 
 
 &lt;p&gt;The &lt;a href=&quot;http://www.who.int/&quot;&gt;World Health Organisation&lt;/a&gt; is 
today urging countries to take action against the spread of 
drug-resistant bacteria, which threaten to deprive us of antibiotics 
which once seemed miracle cures for &lt;a href=&quot;http://www.guardian.co.uk/science/infectiousdiseases&quot; title=&quot;More from guardian.co.uk on Infectious diseases&quot;&gt;infectious diseases&lt;/a&gt;.&lt;/p&gt;&lt;p&gt;The WHO is speaking out following a Lancet paper written by Professor Tim Walsh in the UK and colleagues in &lt;a href=&quot;http://www.guardian.co.uk/world/india&quot; title=&quot;More from guardian.co.uk on India&quot;&gt;India&lt;/a&gt;,
 which warned of the spread of bacteria carrying a new gene, which they 
called NDM 1. These bacteria become resistant to almost all the 
antibiotics designed to fight them. The main piece I wrote about it, 
called &quot;Are you ready for a world without antibiotics?&quot; can be found &lt;a href=&quot;http://www.guardian.co.uk/society/2010/aug/12/the-end-of-antibiotics-health-infections&quot;&gt;here&lt;/a&gt;.&lt;/p&gt;&lt;p&gt;Unfortunately,
 the Indian government reacted badly to the Lancet paper, which 
suggested that one of the factors behind the spread of NDM 1 could be 
medical tourism. Among those in the UK and elsewhere in Europe who were 
found to have these drug-resistant bacterial infections were people who 
had traveled to India for necessary surgery or cosmetic treatment.&lt;/p&gt;&lt;p&gt;An Indian government press release on August 12 said that &lt;/p&gt;&lt;blockquote class=&quot;quoted&quot;&gt;the
 conclusions are loaded with inference that these resistance 
genes/organism possibly originated in India and it may not be safe for 
the UK patients to opt for surgery in India. Concluding sentence 
presents a frightening picture which is not supported by any scientific 
data....such organisms may be circulating more commonly in the world due
 to international travel but to link this with the safety of surgery 
hospitals in India and citing isolated examples to show that due to 
presence of such organism in Indian environment, India is not a safe 
place to visit is wrong.&lt;/blockquote&gt;&lt;p&gt;India has a lot to lose. Medical
 tourism is a boom industry, growing at 30% a year. It would be unfair 
to single it out, because NDM 1 will be elsewhere too. Scientists only 
know it is in India because they have been able to look.&lt;/p&gt;&lt;p&gt;But the 
point the WHO is making today is that no country is any more an island. 
All need to look to their infection control and guard against the wrong 
and cavalier use of antibiotics, such as their sale on the streets 
without prescription, because drug-resistance knows no frontier posts. 
This is what it says:&lt;/p&gt;&lt;blockquote class=&quot;quoted&quot;&gt;Those called 
upon to be alert to the problem of antimicrobial resistance and take 
appropriate action include consumers, prescribers and dispensers, 
veterinarians, managers of hospitals and diagnostic laboratories, 
patients and visitors to healthcare facilities, as well as national 
governments, the pharmaceutical industry, professional societies, and 
international agencies.&lt;p&gt;WHO strongly recommends that governments focus control and prevention efforts in four main areas:&lt;/p&gt;&lt;p&gt;* surveillance for antimicrobial resistance;&lt;br&gt;* rational antibiotic use, including education of healthcare workers and the public in the appropriate use of antibiotics;&lt;br&gt;* introducing or enforcing legislation related to stopping the selling of antibiotics without prescription; and&lt;br&gt;*
 strict adherence to infection prevention and control measures, 
including the use of hand-washing measures, particularly in healthcare 
facilities.&lt;/p&gt;&lt;/blockquote&gt;&lt;p&gt;It ends on a hopeful note:&lt;br&gt;&lt;/p&gt;&lt;blockquote class=&quot;quoted&quot;&gt;&lt;br&gt;Successful
 control of multidrug-resistant microorganisms has been documented in 
many countries, and the existing and well-known infection prevention and
 control measures can effectively reduce transmission of multi-drug 
resistant organisms if rigorously and systematically implemented.&lt;/blockquote&gt;&lt;p&gt;But it&apos;s clear that pretending there is no problem or sitting on our hands is asking for disaster.&lt;/p&gt;

 
 
 &lt;/div&gt;
 

 
 
&lt;/div&gt;</content:encoded>
			<link>https://uhscambodia.ucoz.org/news/who_warns_countries_to_act_against_drug_resistant_bacteria/2010-09-21-9</link>
			<category>External</category>
			<dc:creator>mozachsz</dc:creator>
			<guid>https://uhscambodia.ucoz.org/news/who_warns_countries_to_act_against_drug_resistant_bacteria/2010-09-21-9</guid>
			<pubDate>Tue, 21 Sep 2010 09:00:31 GMT</pubDate>
		</item>
		<item>
			<title>A slice of life</title>
			<description>&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;FROM: http://www.guardian.co.uk/science/blog/2010/sep/16/molecular-complexity-la-rna&lt;br&gt;&lt;/p&gt;&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;The La molecule shows that the deeper you look, the more complicated life becomes &lt;br&gt;&lt;br&gt;&lt;em&gt;&lt;strong&gt;Stephen Curry&lt;/strong&gt; is a professor of structural biology at Imperial College and writes a regular blog at &lt;a href=&quot;http://blogs.nature.com/scurry/&quot; title=&quot;Reciprocal Space&quot;&gt;Reciprocal Space&lt;/a&gt;&lt;/em&gt;&lt;/p&gt;
 
 
 
 
 
 
 


&lt;div id=&quot;content&quot;&gt;

 
 
 


 





 
 

 



 
 

 &lt;div id=&quot;article-wrapper&quot;&gt;

 
 &lt;img src=&quot;http://static.guim.co.uk/sys-images/Guardian/Pix/pictures/2010/9/15/1284566338732/la-protein-006.jpg&quot; alt=&quot;la protein&quot; height=&quot;276&quot; width=&quot;460&quot;&gt;
 N-terminal domain of La complexed with AUUUU RNA. Illustration: Stephen Curry
 
 
 &lt;p&gt;Please don&apos;t be alarmed gentle reader, but I am here to tell you 
that you are an abominable monster. And I have made it my job, like an 
inverse Dr Frankenstein, to di...</description>
			<content:encoded>&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;FROM: http://www.guardian.co.uk/science/blog/2010/sep/16/molecular-complexity-la-rna&lt;br&gt;&lt;/p&gt;&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;The La molecule shows that the deeper you look, the more complicated life becomes &lt;br&gt;&lt;br&gt;&lt;em&gt;&lt;strong&gt;Stephen Curry&lt;/strong&gt; is a professor of structural biology at Imperial College and writes a regular blog at &lt;a href=&quot;http://blogs.nature.com/scurry/&quot; title=&quot;Reciprocal Space&quot;&gt;Reciprocal Space&lt;/a&gt;&lt;/em&gt;&lt;/p&gt;
 
 
 
 
 
 
 


&lt;div id=&quot;content&quot;&gt;

 
 
 


 





 
 

 



 
 

 &lt;div id=&quot;article-wrapper&quot;&gt;

 
 &lt;img src=&quot;http://static.guim.co.uk/sys-images/Guardian/Pix/pictures/2010/9/15/1284566338732/la-protein-006.jpg&quot; alt=&quot;la protein&quot; height=&quot;276&quot; width=&quot;460&quot;&gt;
 N-terminal domain of La complexed with AUUUU RNA. Illustration: Stephen Curry
 
 
 &lt;p&gt;Please don&apos;t be alarmed gentle reader, but I am here to tell you 
that you are an abominable monster. And I have made it my job, like an 
inverse Dr Frankenstein, to dismantle you. The work is exacting, but we 
have to find out what makes you tick, my fearsome friend.&lt;/p&gt;&lt;p&gt;This news may come as a shock, but if you don&apos;t believe me, take a look above.&lt;/p&gt;&lt;p&gt;Appalled
 at yourself? You should be. Your complexity is monstrous. And that is 
just one molecule plucked from among thousands in your body. It goes by 
the disarmingly simple name of La.&lt;/p&gt;&lt;p&gt;If you have ever peered into 
the crowded innards of a computer and recoiled in horror or wonder (the 
two are not so different), you will have some small sense of the task of
 working out the secrets of life. For the intricacies found in human 
artefacts cannot compare to the &lt;a href=&quot;http://blogs.nature.com/scurry/2010/08/30/the-crowded-cell&quot; title=&quot;Reciprocal Space: The crowded cell&quot;&gt;morass of molecules&lt;/a&gt;
 within each one of the trillions of cells in your body. Somehow, this 
crazy jumble of proteins, fats, carbohydrates and nucleic acids (DNA and
 its sibling, RNA) is keeping you alive.&lt;/p&gt;&lt;p&gt;Fortunately, we 
scientists are the monster&apos;s friend. And we are a dogged lot, not put 
off by the unnerving confusion of living things, though we often have to
 focus on the small details to make any headway.&lt;/p&gt;&lt;p&gt;My particular 
task, as a structural biologist, is to uncover the atomic architecture –
 seen in the image above – of the proteins and other molecules that work
 together inside you to sustain life. It is slow, painstaking work. I 
was reminded of this at a conference last week when I stood up to tell 
the audience about our research into the structure of La, which had 
started more than 10 years ago.&lt;/p&gt;&lt;p&gt;La caught my eye back then because
 of reports of its seizure by some viruses, such as hepatitis C virus, 
which force this innocent protein to co-operate with infection. We 
wanted to find out how that happens and, at the same time, to learn more
 about how the protein operates in healthy cells.&lt;/p&gt;&lt;p&gt;La is a tiny cog in the apparatus of life but has an important role in the process of &lt;em&gt;translation&lt;/em&gt; that uses the &lt;a href=&quot;http://en.wikipedia.org/wiki/Genetic_code&quot; title=&quot;Wikipedia: Genetic code&quot;&gt;information in our genes&lt;/a&gt; to make the proteins, the &lt;a href=&quot;http://blogs.nature.com/scurry/2010/08/06/a-molecule-of-life-and-death&quot; title=&quot;Repicrocal Space: A molecule of life and death&quot;&gt;molecular contraptions&lt;/a&gt; that keep your cells alive and communicating with one another.&lt;/p&gt;&lt;p&gt;The
 mechanism of translation uses molecules of RNA – called tRNA – that are
 directly involved in the conversion of the DNA sequence of your genes 
into the chains of amino acids that fold into working proteins. The job 
of La is to ensure that these tRNA molecules are themselves built 
correctly. During tRNA synthesis, La holds on to one end the molecule to
 prevent it becoming damaged by accidental encounters with rogue 
proteins in the cell.&lt;/p&gt;&lt;p&gt;All of this we know by indirect methods, 
feeling blindly with measurements of the strength of the interaction 
between the protein and the RNA. But humans are visual creatures. To 
understand exactly how La embraces a tRNA molecule and how it might be 
ensnared by viral RNA, we have to see the structure of the protein.&lt;/p&gt;&lt;p&gt;Our
 work with La started by transferring the DNA for its gene into bacteria
 that are easily cultured in litres of nutritious soup. This genetic 
trick made it relatively easy to produce large quantities of La protein 
in the lab, entire milligrams of the stuff.&lt;/p&gt;&lt;p&gt;But we then had to 
spend a long time poking and dissecting the protein, testing its 
solubility, checking that it was folded properly, cutting and trimming 
to find a manageable fragment that might be induced to line up in 
orderly ranks to form a crystal, the shining jewel we needed to reveal 
the structure. After many trials and errors (and the distractions of 
securing funding and teaching duties), tiny crystals emerged from our 
experiments. They were 100th of a millimetre thick.&lt;/p&gt;&lt;p&gt;At the &lt;a href=&quot;http://www.diamond.ac.uk/&quot; title=&quot;Diamond synchroton&quot;&gt;Diamond synchrotron&lt;/a&gt; near Oxford &lt;a href=&quot;http://www.youtube.com/watch?v=-taFxGiX1qc&quot; title=&quot;YouTube: X-ray Crystallography at Diamond &quot;&gt;we
 took measurements as the crystals scattered the high-energy beam of 
X-rays in multiple directions, producing patterns of spots on the 
detector. Thanks to the mathematical techniques developed in the19th 
century &lt;/a&gt; by &lt;a href=&quot;http://en.wikipedia.org/wiki/Joseph_Fourier&quot; title=&quot;Wikipedia: Joseph Fourier&quot;&gt;Joseph Fourier&lt;/a&gt;
 (who was grappling with the unrelated problem of heat flow – the 
connections in science are always unpredictable), we were able to use 
the spot pattern to calculate the three-dimensional structure of La, in 
all its atomic glory.&lt;/p&gt;&lt;p&gt;It took years of work, but finally we could &lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430598/?tool=pubmed&quot; title=&quot;PubMed: Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3 Ends by the Human La Protein&quot;&gt;unveil&lt;/a&gt; how part of La (our fragment is just half of the protein) grapples with one end of a tRNA molecule.&lt;/p&gt;&lt;p&gt;We
 have shown how two parts of two of the cogs of life fit together. In 
the grand scheme of things, it is just one small step forward, but it is
 nevertheless an important step, one that shows how the protein 
recognises – by feel, not sight – and protects the tRNA. Thus ensuring 
that the machinery of life keeps ticking over.&lt;/p&gt;&lt;p&gt;This long story is 
still incomplete. There are the remaining portions of La and the tRNA to
 consider. How do they contribute to the protective embrace between 
these two molecules? And is this embrace the same forceful grip by which
 the RNA of hepatitis C virus compels La to sabotage liver cells? To 
tackle these questions we&apos;ve got to spend more years in the lab.&lt;/p&gt;&lt;p&gt;But
 just for a moment, let us pause to admire the horrific complexity of 
your La molecule in action by rendering the protein and RNA chains as 
friendly coils:&lt;/p&gt; &lt;span class=&quot;inline wide&quot;&gt;
 &lt;img src=&quot;http://static.guim.co.uk/sys-images/Guardian/Pix/pictures/2010/9/15/1284566607321/La-protein-cartoon-006.jpg&quot; alt=&quot;La protein (cartoon)&quot; height=&quot;276&quot; width=&quot;460&quot;&gt;
 &lt;/span&gt;
&lt;p&gt;You may be monstrous, dear reader, but I never said you were ugly.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;&lt;em&gt;Stephen Curry&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; is a professor of structural &lt;a href=&quot;http://www.guardian.co.uk/science/biology&quot; title=&quot;More from guardian.co.uk on Biology&quot;&gt;biology&lt;/a&gt; at Imperial College and writes a regular blog at &lt;/em&gt;&lt;a href=&quot;http://blogs.nature.com/scurry/&quot; title=&quot;Reciprocal Space&quot;&gt;&lt;em&gt;Reciprocal Space&lt;/em&gt;&lt;/a&gt;&lt;em&gt;. His work on La is a long-standing collaboration with Dr Maria Conte at King&apos;s College London&lt;/em&gt;&lt;/p&gt;

 
 
 &lt;/div&gt;
 

 
 
&lt;/div&gt;</content:encoded>
			<link>https://uhscambodia.ucoz.org/news/a_slice_of_life/2010-09-21-8</link>
			<category>External</category>
			<dc:creator>mozachsz</dc:creator>
			<guid>https://uhscambodia.ucoz.org/news/a_slice_of_life/2010-09-21-8</guid>
			<pubDate>Tue, 21 Sep 2010 08:51:16 GMT</pubDate>
		</item>
		<item>
			<title>Obesity crisis &apos;cannot be solved by exercise alone&apos;</title>
			<description>&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;FROM: http://www.guardian.co.uk/society/2010/sep/15/obesity-crisis-cannot-solved-exercise&lt;br&gt;&lt;/p&gt;&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;Study urges severely obese to eat more healthily, finding that forgoing a small sandwich is as effective as a one-hour run&lt;/p&gt;&lt;div id=&quot;content&quot;&gt;

 
 
 

 




&lt;ul class=&quot;article-attributes&quot;&gt;&lt;li class=&quot;byline&quot;&gt;
 &lt;a class=&quot;contributor&quot; href=&quot;http://www.guardian.co.uk/profile/iansample&quot;&gt;Ian Sample&lt;/a&gt;, science correspondent
 &lt;/li&gt;&lt;li class=&quot;publication&quot;&gt; 
 &lt;a href=&quot;http://www.guardian.co.uk/&quot;&gt;guardian.co.uk&lt;/a&gt;, 
 
 Wednesday 15 September 2010 20.24 BST 
 &lt;/li&gt;&lt;li class=&quot;history&quot;&gt;&lt;a class=&quot;rollover history-link&quot; id=&quot;history-link-byline&quot; href=&quot;http://www.guardian.co.uk/society/2010/sep/15/obesity-crisis-cannot-solved-exercise#history-link-box&quot;&gt;Article history&lt;/a&gt;&lt;/li&gt;&lt;/ul&gt;

 





 
 

 



 
 

 &lt;div id=&quot;article-wrapper&quot;&gt;

 
 &lt;img src=&quot;http://static.guim.co.uk/sys-images/Guardian/Pix/pictures/2010/9/15/...</description>
			<content:encoded>&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;FROM: http://www.guardian.co.uk/society/2010/sep/15/obesity-crisis-cannot-solved-exercise&lt;br&gt;&lt;/p&gt;&lt;p id=&quot;stand-first&quot; class=&quot;stand-first-alone&quot;&gt;Study urges severely obese to eat more healthily, finding that forgoing a small sandwich is as effective as a one-hour run&lt;/p&gt;&lt;div id=&quot;content&quot;&gt;

 
 
 

 




&lt;ul class=&quot;article-attributes&quot;&gt;&lt;li class=&quot;byline&quot;&gt;
 &lt;a class=&quot;contributor&quot; href=&quot;http://www.guardian.co.uk/profile/iansample&quot;&gt;Ian Sample&lt;/a&gt;, science correspondent
 &lt;/li&gt;&lt;li class=&quot;publication&quot;&gt; 
 &lt;a href=&quot;http://www.guardian.co.uk/&quot;&gt;guardian.co.uk&lt;/a&gt;, 
 
 Wednesday 15 September 2010 20.24 BST 
 &lt;/li&gt;&lt;li class=&quot;history&quot;&gt;&lt;a class=&quot;rollover history-link&quot; id=&quot;history-link-byline&quot; href=&quot;http://www.guardian.co.uk/society/2010/sep/15/obesity-crisis-cannot-solved-exercise#history-link-box&quot;&gt;Article history&lt;/a&gt;&lt;/li&gt;&lt;/ul&gt;

 





 
 

 



 
 

 &lt;div id=&quot;article-wrapper&quot;&gt;

 
 &lt;img src=&quot;http://static.guim.co.uk/sys-images/Guardian/Pix/pictures/2010/9/15/1284578640326/Fat-woman-obese-obesity-006.jpg&quot; alt=&quot;Fat woman obese obesity&quot; height=&quot;276&quot; width=&quot;460&quot;&gt;
 &lt;br&gt;&lt;br&gt;The obesity crisis will not be solved by exercise 
alone, according to a new study from Aberdeen University. Photograph: 
Jose Luis Pelaez/Getty Images/Blend Images
 
 
 &lt;p&gt;The &lt;a href=&quot;http://www.guardian.co.uk/society/obesity&quot; title=&quot;More from guardian.co.uk on Obesity&quot;&gt;obesity&lt;/a&gt; epidemic will not be reversed by urging people to exercise more, because they have too little time to spare, researchers claim.&lt;/p&gt;&lt;p&gt;To
 make an impact on levels of obesity, severely overweight people would 
have to exercise for several hours a day, when they could find it easier
 to lose the weight by eating less, they said.&lt;/p&gt;&lt;p&gt;An obese person 
with a body mass index of 35 could reach a more healthy weight and BMI 
of 22 by reducing their calorie intake by one third. &quot;That is equivalent
 to exercising for around five hours a day. That is not realistic,&quot; said
 Professor John Speakman of the energetics research group at Aberdeen 
University.&lt;/p&gt;&lt;p&gt;A study by Speakman&apos;s group found that contrary to 
popular belief, our lives have not become more sedentary in recent 
decades. Physical activity has remained the same for at least the past 
25 years, while obesity rates have soared.&lt;/p&gt;&lt;p&gt;Since 1985, the typical
 man in Britain has burned off 1,380 calories a day through exercise, 
compared with 950 calories for women. The cause of rising obesity is 
linked to the population eating more high-calorie food than exercising 
less, Speakman said.&lt;/p&gt;&lt;p&gt;&quot;Promoting exercise is a good idea, but if 
you want to tackle the obesity epidemic it is not the solution. Weight 
loss is not a key benefit from exercise,&quot; he said. Foregoing a small 
sandwich was as effective as a one-hour run, he added.&lt;/p&gt;&lt;p&gt;About a 
quarter of British adults and a fifth of children are obese and this 
figure is rising. An estimated 30,000 people die prematurely across the 
country from obesity-related illnesses each year.&lt;/p&gt;&lt;p&gt;&quot;You cannot 
exercise your way out of the obesity epidemic. It would take an enormous
 intervention in physical exercise,&quot; Speakman said.&lt;/p&gt;&lt;p&gt;&quot;It is 
important for policymakers to realise that if they want to promote 
weight loss in overweight and obese people, the most effective way is 
through healthy eating and diets.&quot;&lt;/p&gt;&lt;p&gt;However, the report says exercise protects against heart disease, type 2 diabetes, osteoporosis and high blood pressure.&lt;/p&gt;

 
 
 &lt;/div&gt;
 

 
 
&lt;/div&gt;</content:encoded>
			<link>https://uhscambodia.ucoz.org/news/obesity_crisis_cannot_be_solved_by_exercise_alone/2010-09-21-7</link>
			<category>External</category>
			<dc:creator>mozachsz</dc:creator>
			<guid>https://uhscambodia.ucoz.org/news/obesity_crisis_cannot_be_solved_by_exercise_alone/2010-09-21-7</guid>
			<pubDate>Tue, 21 Sep 2010 08:47:52 GMT</pubDate>
		</item>
	</channel>
</rss>